Methylation support from within.
TMG supplies methyl groups used within the body’s natural methylation pathways, supporting homocysteine metabolism, methionine recycling and normal cellular processes.
Support cellular energy, healthy methylation, and overall wellbeing with our premium Trimethylglycine (TMG) formula. Powered by our exclusive Enteric Sustained-Release Formula®, it is designed to bypass stomach acid and gradually release TMG in the small intestine, providing steady support for methylation, homocysteine metabolism, and daily performance. Often paired with NMN, TMG helps support healthy methylation as part of the body’s natural NAD+ metabolic processes, making it an excellent complement to your longevity routine.
Why You'll Love It






Trimethylglycine, commonly known as TMG or betaine, is a naturally occurring methyl donor that supports healthy methylation, normal homocysteine metabolism and everyday cellular function.
TMG supplies methyl groups used within the body’s natural methylation pathways, supporting homocysteine metabolism, methionine recycling and normal cellular processes.
Provides methyl groups used within normal methylation and methionine-cycle pathways.
Supports the normal conversion of homocysteine back into methionine.
Supports cellular processes involved in normal metabolism, energy production and everyday performance.
Designed to help protect the capsules as they pass through the stomach before releasing gradually further along the digestive tract.
The enteric format is designed to help protect the capsules during their passage through the stomach.
The capsules are designed to begin releasing further along the digestive tract rather than immediately in the stomach.
Sustained-release design supports a more gradual delivery compared with a conventional immediate-release format.
Our TMG has been designed around a practical daily serving, a considered sustained-release capsule format and a simple routine that is easy to maintain.
Designed for protected passage through the stomach followed by gradual release further along the digestive tract.
Two capsules provide a total daily serving of 1200 mg trimethylglycine.
Provides dedicated methylation support that can complement a wider NMN and cellular-wellness routine.
Manufactured in a GMP production environment using controlled processes and defined quality standards.
Take two capsules daily or follow the directions shown on the product label. Swallow the capsules whole to preserve the enteric sustained-release format.
Two capsules provide a total daily serving of 1200 mg trimethylglycine.
Do not open, crush or chew the capsules, as this may interfere with the sustained-release format.
Designed to support methylation, homocysteine metabolism and normal cellular function.
Learn more about TMG (Betaine Anhydrous), the methylation cycle, our Enteric Sustained-Release Formula® and how to make it part of your daily wellness routine.
Trimethylglycine, commonly known as TMG or Betaine Anhydrous, is a naturally occurring compound found in foods such as beets and spinach.
In the body, TMG functions as a methyl donor, supplying methyl groups to normal cellular processes, including those involved in the methylation cycle.
Methylation is a normal biochemical process the body relies on for everyday cellular function, including the conversion of homocysteine back into methionine.
TMG supplies a methyl group for this conversion, which is why it is often researched alongside other methyl donors and cofactors involved in the same pathway.
Yes. TMG and Betaine Anhydrous refer to the same compound. "Trimethylglycine" describes its chemical structure, while "Betaine" is the common name most often seen on labels.
AlphaMens Lab uses Betaine Anhydrous, a purified, non-hygroscopic form suited to stable capsule manufacturing.
Our enteric sustained-release format is designed to help protect the capsule as it passes through the stomach before beginning to release further along the digestive tract.
The sustained-release design then supports a more gradual delivery compared with a conventional immediate-release capsule format.
Take two capsules daily as one serving, or follow the directions shown on the product label. Each capsule provides 600 mg of TMG (Betaine Anhydrous), for a total of 1200 mg per serving.
Each bottle contains 90 capsules, providing 45 servings. Swallow the capsules whole with water. Do not open, crush or chew them, as doing so may interfere with the enteric sustained-release format.
TMG can be taken at a time that fits consistently into your daily routine, with or without food. Some people prefer taking both capsules together, others split them across two meals.
Consistent use according to the label directions is generally more important than taking it at one exact time.
TMG is commonly paired with NMN because NAD+ production pathways draw on the body's methyl group supply, and TMG acts as a methyl donor.
Many people incorporate both as part of the same daily routine, following the directions on each product's label.
TMG may be incorporated alongside other everyday supplements, but individual combinations should be considered carefully.
Check the ingredient panels of your supplements to avoid unnecessary duplication. Seek professional advice if you take medication or use multiple specialised products.
Store the bottle in a cool, dry place away from direct sunlight, heat and moisture. Keep the lid tightly closed when the product is not in use.
Always follow any additional storage instructions shown on the product label.
Consult a healthcare professional before use if you are pregnant or breastfeeding, have an existing medical condition, take prescription medication or are preparing for surgery.
Discontinue use and seek professional advice if you experience an adverse reaction.